A. Not all facial fillers can be dissolved. We prefer to use fillers in the face that can be dissolved, especially in areas of the face where there are significant blood vessels. Permanent fillers such as Bellafil and Silicone cannot be dissolved at all. Radiesse, though not a permanent filler, cannot be dissolved. The fillers that are made up of hyaluronic acid (Restylane, Juvederm, Voluma, Belotero) can be dissolved with an injection of hyaluronidase, an enzyme that rapidly breaks down the filler. The advantages of fillers that can be dissolved are that any lumps, bumps, or filling that is not good can be quickly corrected, and in the rare case of filler being injected into a blood vessel with vascular compromise, impending vascular necrosis can be avoided. Sculptra is a biological collagen stimulating filler that cannot be dissolved, yet is very safe as the fine Sculptra particles are dissolved in water and local anesthetic solution. My philosophy is to avoid the use of permanent fillers in the face because if there is a problem it can be very difficult to take care of….”Permanent filler, permanent problems.” Good luck and be well. ~Dr. P